THE STUDY OF PATHOPHYSIOLOGICAL LINK OF AUTOIMMUNIZATION IN PATIENTS WHO USE SOFT CONTACT LENSES

  • I.Yu. Bagmut Kharkiv Medical Academy of Postgraduate Education, Kharkiv
  • O.A. Kuzmenko Kharkiv Medical Academy of Postgraduate Education, Kharkiv
  • A.V. Titkova
Keywords: immune system, soft contact lenses, normal microflora

Abstract

In this work, the state of the immune system was studied in thepatients using soft contact lenses for various variants of the normal microflora eyes. Analyzing the absolute number of lymphocytes in the peripheral blood, we found that these indices are within the limits of normal physiological fluctuations and do not have a significant difference between the groups. The same tendency was observed in the study of the content of common T-lymphocytes, and their number in all groups is within the limits of normal physiological parameters. The inhibition of the IL-2 expression activator confirms our assumption of latent suppression of the T-immune system, especially in patients who have a smoking habit. It has been found that in patients who use soft contact lenses and have a habit of smoking there is a decrease in the level of B-lymphocytes. However, despite the normal immunological parameters of B-lymphocytes, in the 1st group as well as in the 2nd group there is a hidden inhibition of the T-immune system.

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Published
2017-11-28
How to Cite
Bagmut, I., Kuzmenko, O., & Titkova, A. (2017). THE STUDY OF PATHOPHYSIOLOGICAL LINK OF AUTOIMMUNIZATION IN PATIENTS WHO USE SOFT CONTACT LENSES. The Medical and Ecological Problems, 21(3-4), 14-17. Retrieved from https://ecomed-journal.org/index.php/journal/article/view/82

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