Ethical Guidelines

When reporting experiments on human subjects, authors should indicate whether the procedures were performed in accordance with the ethical standards of Helsinki Declaration of the World Medical Association of 1975 as revised in 2013. Therefore, the manuscript must include the following clause: “We declare that during research the rights of patients were taken into consideration according to Helsinki Convention”. If doubts for that matter arise, authors must account for the doubtful aspects of the study and explain the reasons for their approach.

Authors must follow the principles of humane attitude to animals used in experiments. When reporting experiments on animals, authors should indicate whether the institutional and national guides for care and use of laboratory animals were respected. They must submit the following information: type of animals, genetic status: the line (according to standard rules of defining the lines of laboratory animals); the category of laboratory animals or their microbiological status; weight and age of animals at the beginning of the experiment; quarantine or acclimatization period during transportation over long distances; maintenance conditions during the experiment (microclimate parameters, temperature, humidity, air volume, light conditions, cage type, type of bedding material). Authors must prove the compliance with normative standards on animals maintenance and foddering (European Convention for the Protection of vertebral animals used in experiments or other purposes. – Strasbourg, 1986) and provide the information as to the acquisition source of animals, as well as the quality certificate. It is necessary to describe all procedures performed on animals, introduced doses of medications, surgical interventions and other actions, the use of anesthesia methods (see Statement of Human and Animal Rights). If the research does not involve experiments on laboratory animals, the article must include the following statement: “We declare that we do not perform research on animals”.

When describing medical case reports, to increase the completeness, accuracy and transparency of published reports on new or rare diseases, as well as innovative therapeutic approaches, use the checklist https://www.care-statement.org/checklist of the EQUATOR Network standard: CARE guideline for consensus reporting of clinical cases.