TY - JOUR AU - Taktashov, G.S. PY - 2017/03/21 Y2 - 2024/03/29 TI - ASSOCIATION BETWEEN RESPIRATORY DYSFUNCTION AND ATMOSPHERE POLLUTION IN CHRONIC RHEUMATIC HEART DISEASE JF - The Medical and Ecological Problems JA - Med. and Ecol. probl. VL - 19 IS - 1-2 SE - ENVIRONMENTAL ASPECTS DO - UR - https://ecomed-journal.org/index.php/journal/article/view/37 SP - 25-27 AB - The prevalence of chronic rheumatic heart disease (CRHD) depends on ecology of environment. The aim of our research is to estimate clinic pathologic roles of aeropollutants in case of respiratory dysfunction of such patients. Material and methods. There were 474 patients with CRHD under observation (33% men and 67% women) at the age from 16 to 66 years old. We estimated the impact of discharge to the atmosphere of xenobiotics, the concentration of ammonia in the air, benzpyrene, dioxides С, N, S, oxide C, hydrogen sulphide and phenol, and also the integral atmosphere pollution with pollutants (IQA) on the parameters of ventilation, moisture separating, diffusion, and surfactant producing lung function. Results. Patients with CRHD living in the cities breathe in the air with benzpyrene concentration which is 3.6 times higher than in the country side. The concentration of dioxides С, N, S, is 2.3, 2.1 and 2.0 times higher respectively. The concentration of hydrogen sulphide is higher by 83%, oxide C by 59% and phenol by 50%. IQA defines the integral parameters of breathing capacity, bronchial permeability and surfactant functions of lungs in accordance with the assessment of physicochemical characteristics of condensate of expiratory air. The condition of alveolar-capillary membrane is defined by the content of ammonia in the atmosphere, dioxide C and phenol, and expiratory moisture separating depends on the level of benzpyrene and hydrogen sulphide. The content of dioxide C and IQA are the prognostic indicators in relation with respiratory abnormalities. Conclusion: atmosphere pollution of patients’ living zones with xenobiotics affects the respiratory dysfunction in case of CRHD. ER -