TY - JOUR AU - Ruzhanska, V.O. AU - Sivak, V.G. AU - Lozinska, M.S. AU - Zhebel, V.М. PY - 2018/03/20 Y2 - 2024/03/28 TI - GALECTIN-3 AS A MARKER OF MYOCARDIAL FUNCTION IN MEN AGED 40-60 YEARS WITHOUT CARDIOVASCULAR PATHOLOGY, CARRIERS OF POLYMORPHIC GENES AT1R JF - The Medical and Ecological Problems JA - Med. and Ecol. probl. VL - 22 IS - 1-2 SE - CLINICAL MEDICINE DO - 10.31718/mep.2018.22.1-2.08 UR - https://ecomed-journal.org/index.php/journal/article/view/117 SP - 38-42 AB - The concentrations of galectin-3 and BNP, central and systemic hemodynamics, structural and functional heart parameters in male carriers of polymorphic AT1R genes without cardiovascular pathology (n = 79) living in Podillya region were studied. Genotyping of the AT1R gene was carried out using a polymerase chain reaction. The level of galectin-3 and BNP was determined by the method of enzyme immunoassay. It was found that the A1166A genotype dominated in practically healthy men of Podilly region. Nevertheless, the level of galectin-3 and BNP in the studied population did not significantly depend on the carriage of a specific variant of the AT1R gene. ER -