ENVIRONMENTAL CONDITIONALITY OF BREAST CANCER MORBIDITY IN WOMEN RESIDING IN INDUSTRIALIZED AREAS

  • T.V. Pyatchanina R.Ye. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine
  • A.N. Ohorodnyk R.Ye. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine
  • O.S. Dvorschenko R.Ye. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine
  • M.Y. Zarytska R.Ye. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, National Academy of Sciences of Ukraine, Kyiv, Ukraine
Keywords: environment, risk factors, breast cancer, ionizing radiation, pollutants, chemical carcinogens

Abstract

The role of factors of environmental conditionality of breast cancer in women living in the ecologically polluted areas of Ukraine and other former USSR republics of the European part is highlighted. Regulatory parameters are presented for the main environmental pollutants with etiopathogenetic role in the development of breast cancer.

Downloads

Download data is not yet available.

References

1. Antipova S.I., Gender issues in Belarus Oncology / S.I. Antipova, V.V. Antipov, N.G. Shebeko // Medical News. - 2013. – No. 3. – P. 31–41.
2. Bukharitsin P.I., Assessment of the current state of water resources of the continental regions of the globe // Geology, Geography and Global Energy. - 2011. – No. 1 (40). – P. 121–132.
3. Bulletin of the National Cancer Registry No. 16. – Cancer in Ukraine 2012-2013. / National Cancer Institute, Kyiv, 2015. – 127 p.
4. Emissions of pollutants into the air in the Russian Federation [Electronic resource]. – Access: http://www.gks.ru/wps/wcm/connect/rosstat_main/rosstat/ru/statistics/environment/, free. – (Date of retrieve: 11.03.2003).
5. GOST 3034-84, 3210-85, 42-128-4433-87 "Maximum permissible concentrations of harmful substances in soils." – [Electronic resource]. – Access: http://agromage.com/stat_id.php?id=577 – (Date of treatment: 15.02.2003).
6. GN No. 187 dated 06.11.2008 "Maximum permissible concentrations (MPCs) of the mobile forms of chromium, zinc and cadmium in the soil (land) of various functional areas of human settlements, industry, transport, communications, energy, defense and other purposes. – [Electronic resource] – Access: http://www.busel.org/texts/cat2na/id5qwmfng.htm – (Date of retrieve: 11.02.2003).
7. GN 1.1.725-98. List of substances, products, production processes, domestic and natural factors, which are carcinogenic for humans. – Publishing house: Science, 1998. – 27 p.
8. DSP No. 201-97. State sanitary rules of protection of atmospheric air in populated areas from contamination by harmful chemical and biological agents. – Publishing house: Science, 1997. – 34 p.
9. WHO report on the situation in the area of non communicable diseases in the world, 2010 – 2013 – 184 p.
10. Uniform sanitary/epidemiological and hygienic requirements for goods subject to sanitary/epidemiologic supervision (control) dated 02.03.2011. – No. 571. – 1011 p.
11. Zvyagintsev A.V. Hazard assessment of air pollution of industrial cities of Ukraine / A.V Zvyagintsev. // Geotechnical Mechanics. - 2013. – No. 109. – P. 233.
12. Cadmium[Electronic resource]. – Access: http://www.euro.who.int/__data/assets/pdf_file/0016/123073/AQG2ndEd_6_3Cadmium.PDF, free. – (Date of retrieve: 5.04.2015).
13. Kiriushin V.A., Motalova T.V., Safonkin S.V. Chemical Toxicology: hazardous materials and activities in the centers of chemical damage. – Ryazan: Russian State Medical University, 2004. – 163 p.
14. Codex Alimentarius [Electronic resource]. – Access: http://www.codexalimentarius.org, free. – (Date of retrieve: 11.03.2003).
15. Kuligina E.Sh. Epidemiological and molecular aspects of breast cancer / E.Sh. Kuligina // Practical Oncology. - 2010. – V. 11. – No. 4. – P. 203–216.
16. National Report on the State of Environment in Ukraine in 2011. – K.: Ministry of Ecology and Natural Resources of Ukraine, 2012. – 258 p.
17. National Statistical Committee of the Republic of Belarus [Electronic resource]. – Access: http://belstat.gov.by/ofitsialnaya-statistika/otrasli-statistiki/okruzhayuschaya-sreda/, free. – (Date of retrieve: 11.03.2003).
18. Neumerzhitsky V.A. The relative risk of breast cancer with concurrent somatic pathology in female liquidators of the Chernobyl accident / V.A. Neumerzhitsky, T.A. Kozlov, K.V. Moschik // Medical News. - 2003. – No. 6. – P. 66–68.
19. NRBU-97. State Hygienic standards. Radiation Safety Standards of Ukraine dated 01.12.97. – K.: Naukova Dumka, 1998. – 121 p.
20. Review of the problem of environmental pollution with cadmium, lead and mercury, 2008. – [Electronic resource]. – Access: http://www.who.int/ifcs/documents/forums/forum6/eco_accord_ru.pdf, free. – (Date of retrieve: 04.01.2015).
21. Evaluation of the risk of breast cancer [Electronic resource]. – Access http://www.womenshealthsection.com/content/print.php3?title=gyno018&cat=41&lng=russian, free. – (Date of retrieve: 11.03.2003).
22. The list of maximum permissible concentrations (MPC) and approximate permissible concentrations (APC) of chemical substances: hygienic standards 2.1.7.12-1-2004. Minsk, 2004. – 48 p.
23. Prodanchuk N.G. The role of organochlorines in the formation of breast pathology / N.G. Prodanchuk, R.A. Moiseenko // Modern Problems of Toxicology. - 2010. – No. 1. – P. 7–16.
24. Reichman Y.G. Theoretical Foundations of Cancer Prevention, 2009. – 350 p.
25. Commission Regulation (EC) No. 1881/2006 setting the maximum levels for certain contaminants in food stuffs. – Official Journal of the European Union, 2006. – 28 p.
26. Romanyuk A.M. Morphological and biochemical characteristics of breast cancer in terms of pollution with salts of / A.M. Romaniuk, M.S. Lyndin // Bulletin of Biology and Medicine Problems. - 2014. – Issue 4 – Vol. 1 (113). – P. 318–322.
27. Sanitary Standards SanPiN 42-128-4433-87 "Sanitary standards of permissible concentrations of chemicals in the soil." – Publishing house: State Statistics Committee, 1987. – 37 pp.
28. Sanitary Rules SanPiN 4630-88 "Sanitary rules and norms for surface waters protection from pollution." – M., 1988. – 59 p.
29. Sosnovskaya E.Y. The risk of developing breast cancer after exposure to ionizing radiation from the Chernobyl disaster / E.Y. Sosnovskaya, O.F. Semenenko, A.A. Silina // Medical News. - 2006. – No. 3. – P. 31–36.
30. Suleimanov E.V. Korshunov A.O. Modern Environmental Problems. – Nizhny Novgorod: Nizhny Novgorod State University, 2012. – 29 p.
31. Technical Regulations of the Customs Union 021/2011 "On Food Safety" , 2011. – 242 p.
32. Toxic trace elements and heavy metals (Hg, Cd, As, Li, Pb, Al). [Electronic resource]. – Access http://www.helix.ru/kb/item/06-232, free. – (Date of retrieve: 25/02/2015).
33. Chasova E.V. Dioxins as an environmental hazard / E.V. Chasova, L.D. Ermak // Vesnik KTU. Technical Sciences – 2010. – Issue. 25. – P. 158–165.
34. Chumak AA Health effects of the Chernobyl disaster in Ukraine. – Chernobyl: Ecology, Man, Health. / Coll. materials. – M.: Nuclear Safety Institute, 2006. – P. 60–64.
35. Shamrai OV Malignant neoplasms: territorial and socio-medical aspects / O.V. Shamrai, P.Y. Odarchenko // Vinnytsya: “Publishing House of Vinnytsya”, 2002. – 78 pp.
36. Shamrai O.V. Hygienic assessment of regional ecological characteristics of the environment and their role in the formation of regional differences in cancer pathology of the population of Ukraine: author's abstract of the Ph.D. thesis. Techn. Sciences. – D., 2003. – 17 p.
37. Schwager O.V. Hygienic evaluation of carcinogenic air pollution of cities with varying profiles of industry / O.V. Schwager, I.O. Chernichenko // Protection of the Environment and Health. Proceedings. – 2013. – No. 3. – P. 9–13.
38. Akesson A. Long­term dietary cadmium intake and postmenopausal endometrial cancer incidence: a population­based prospective cohort study / A. Akesson, B. Julin // Cancer Res, 2008. – 68. – Р. 6435–6441.
39. Alatise O. Lead exposure: a contributing cause of the current breast cancer epidemic in Nigerian women / O. Alatise, G. Schrauzer // Biol Trace Elem Res. – 2010. – 136(2). – Р. 127–139.
40. Bettina J., Alicja W. Dietary Cadmium Exposure and Risk of Postmenopausal Breast Cancer: A Population-Based Prospective Cohort Study // Cancer Res. - 2012. – 72. – P. 1459–1466.
41. Collins J. Body mass index and serum ch6lorinateddibenzo-p-dioxin and dibenzofuran levels / J. Collins, K. Bodner // Chemosphere. - 2007. – 66. – Р. 1079–1085.
42. Dip R. Genetic reprogramming of human mammary cells by environmental carcinogens released into breast milk. / R. Dip, T. Buerin // Chimia. - 2008. – 62. – Р. 410–416.
43. Hankinson S. Endogenous estrogen, testosterone and progesterone levels in relation to breast cancer risk. / S. Hankinson, A. Eliassen // The Journal of Steroid Biochemistry and Molecular Biology. - 2007. – 106. – Р. 24–30.
44. Health assessment document for 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds // US Environmental Protection Agency Office of Health and Environmental Assessment, Office of Research and Development. – Vol. 13. – Washington, 1994.
45. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Vol. 1-83. Lyon France, 2006. – Eng., Fran. [Electronic resource]. – Access: http://monographs.iarc.fr/ENG/Monographs/PDFs/index.php, free. – (Date of retrieve: 12.03.2015).
46. Kortenkamp A. Are cadmium and other heavy metal compounds acting as endocrine disrupters. // Metal Ions in Life Sciences. - 2011. – 8. – P. 305–317.
47. Latest world cancer statistics. International Agency for Research on Cancer, 2013. -№223. [Electronic resource]. – Access: http://globocan.iarc.fr/Default.aspx – (Date of retrieve: 11.03.2003).
48. Little JB Radiation carcinogenesis / Carcinogenesis. - 2000. – No. 21(3). – P. 397–404.
49. Loreta Strumylaite, Algirdas Bogusevicius, Olegas Abdrachmanovas, Dale Baranauskiene, Rima Kregzdyte, Darius Pranys, Lina PoskieneCadmium concentration in biological media of breast cancer patients // Breast Cancer Research and Treatment. – 2011. – Vol. 125. – Issue 2. – P. 511–517.
50. Mastalers P. The true story of DDT, PCB and dioxins. – Wroclav : Wyd. Chemiczne, 2005. – P. 165
51. Otto G. Raabe Ionizing Radiation Carcinogenesis. INTECH Open Access Publisher, 2012. – P. 299–348.
52. Pasha Q. Comparative evaluation of trace metal distribution and correlation in human malignant and benign breast tissues. // Biological Trace Element Research Stephen Juma Mulware. The Mammary Gland Carcinogens: The Role of Metal Compounds and Organic Solvents. International Journal of Breast Cancer, 2013. – P. 10
53. Polychlorinated dibenzo-para-dioxins and polychlorinated dibenzofurans. Vol. 69. Lyon, France: IARC Press, 1997. – Р. 333–344.
54. Polynuclear Aromatic Hydrocarbons. In: Guidelines for Drinking-water Quality, 2nd ed. Vol. 2. Health Criteria and other Supporting Information . – 2003. – P. 32
55. Prashant S. Dioxins sources and current remediation technologies – a review. // Environment International. - 2008. – Vol. 34. – Is. 1. – P. 139–153.
56. Revich B. The dioxin pollution as a risk of development female breast cancer. / B. Revich, T. Ushakova // Organohalogen compounds, Russia. - 2002. – Vol. 59. – Р. 361–364.
57. Revich B. Dioxin exposure and public health in Chapaevsk, Russia. // Chemosphere. - 2001. – Vol. 43. – P. 951–966.
58. Pukkala E. Breast cancer in Belarus and Ukraine after the Chernobyl accident. [Electronic resource]. – Access:http://onlinelibrary.wiley.com/doi/10.1002/ijc.21885/epdf – (Date of retrieve: 11.03.2015).
59. Russo J. Developmental, cellular, and molecular basis of human breast cancer / J. Russo, Y. Hu // J. Natl. Cancer Inst. Monogr. - 2000. – Vol. 27. – P. 17–37.
60. Reynolds P. Adipose levels of dioxins and risk of breast cancer. / P. Reynolds, S. Hurley // Cancer Causes Control. - 2005. – 16(5). – P. 525–535.
61. State of the Science of Endocrine Disrupting chemicals, 2012. [Electronic resource]. – Access: http://www.who.int/ceh/publications/endocrine/en/ – (Date of retrieve: 11.03.2015).
62. Some non-heterocyclic polycyclic aromatic hydrocarbons and some related exposures / IARC Monogr Eval Carcinog Risks Hum. - Lyon, France, 2010. – Vol. 92. – 853 p.
63. Some industrial chemicals / IARC MonogrEvalCarcinog Risks Hum. – Lyon, France, 2000. – Vol. 77. – 573 p.
64. Stephen J. The Mammary Gland Carcinogens: The Role of Metal Compounds and Organic Solvents. [Electronic resource]. – Access: http://dx.doi.org/10.1155/2013/640851 – (Date of retrieve: 21.03.2015).
65. Warner M. Serum dioxin concentrations and breast cancer risk in the Seveso women's health study. / M. Warner, B. Eskenazi, P. Mocarelli // Environ Health Perspect. - 2002. – Vol. 110. – P. 625–628.
66. Weir R. Risk factors for breast cancer in women / R. Weir, P. Day, W. Ali // NZHTA Report. - 2007. – 10(2). – 361 р.
67. Welsch CW Host factors affecting the growth of carcinogen-induced rat mammary carcinomas: a review and tribute to Charles Brenton Huggins. Cancer Res., 1985. – 45. – P. 3415–3440.
68. World Cancer Report. Edited by Bernard W. Stewart and Christopher P. Wild. – [Electronic resource]. – Access: http://apps.who.int/bookorders/anglais/detart1.jsp?codlan= 1&codcol=76&codcch=31 – (Date of retrieve: 30.03.2003).
Published
2018-07-06
How to Cite
Pyatchanina, T., Ohorodnyk, A., Dvorschenko, O., & Zarytska, M. (2018). ENVIRONMENTAL CONDITIONALITY OF BREAST CANCER MORBIDITY IN WOMEN RESIDING IN INDUSTRIALIZED AREAS. The Medical and Ecological Problems, 19(1-2), 17-21. Retrieved from https://ecomed-journal.org/index.php/journal/article/view/35